SubjectsSubjects(version: 954)
Course, academic year 2023/2024
  
Toxicology and Ecotoxicology I - B240001
Title: Toxikologie a ekotoxikologie I
Guaranteed by: Department of Environmental Chemistry (240)
Faculty: Faculty of Environmental Technology
Actual: from 2022 to 2023
Semester: both
Points: 3
E-Credits: 3
Examination process:
Hours per week, examination: 2/0, Ex [HT]
Capacity: winter:unlimited / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Level:  
Additional information: http://Předmět je vyučován pouze v zimním semestru. Zkoušky se konají u přednášejících.
Old code: ZTOE
Note: you can enroll for the course in winter and in summer semester
Guarantor: McGachy Lenka Ing. Ph.D.
Interchangeability : N111009, N240011, Z240011
This subject contains the following additional online materials
Annotation -
Toxicology and Ecotoxicology I is a course that provides basic information about substances that harm living organisms. The course generally covers the fundamentals of toxicokinetics and toxicodynamics, experimental evaluation of toxicity, and a summary of basic information on the toxicology of selected xenobiotics (including inorganic and organic xenobiotics, environmental contaminants, warfare and addictive substances, and natural toxins). It also includes a lecture dealing with the abiotic and biotic components of the ecosystem and the flow of substances and energy in nature. Another lecture is devoted to general principles of first aid for chemical exposure and health protection in chemical workplaces.
Last update: McGachy Lenka (03.05.2024)
Aim of the course -

Students completing this course will acquire a fundamental understanding of substances that harm living organisms and will grasp the basic principles of toxicokinetics and toxicodynamics. They will gain insight into experimental toxicity assessment and receive an overview of the toxicology of selected xenobiotics, encompassing inorganic and organic xenobiotics, environmental contaminants, warfare and addictive substances, and natural toxins. Additionally, they will comprehend the abiotic and biotic components of the ecosystem and the flow of substances and energy in nature. Moreover, they will be familiar with the general principles of first aid for chemical exposure and health protection in chemical workplaces.

Last update: McGachy Lenka (03.05.2024)
Literature -

Z:

I. Linhart: Basic Terms in Toxicology, Ecology and Ecotoxicology (A bilingual textbook). UCT Press, UCT Prague 2019.

Online: https://vydavatelstvi.vscht.cz/katalog/publikace?uid=uid_isbn-978-80-7592-040-9

D:

S. Kacew and B.-M-Lee, editors: Lu's Basic Toxicology. Fundamentals, Target Organs, and Risk Assessment. 6th edition, CRC Press 2012; ISBN: 13:978-1-841849539; 10:978-1-841849537); Chapters 1 - 4, 7, 20, 23 and 24.

S. E. Manahan: Toxicological Chemistry and Biochemistry. 3rd edition, Lewis Publishers 2003; ISBN:1-56670-618-1

S.E. Manahan: Fundamentals of Environmental and Toxicological Chemistry. 4th edition, CRC Press 2013;978-1-4665-5316-3

Gilbert Steven G.: A Small Dose of Toxicology, The Health Effects of Common Chemicals, Informa Healthcare USA, 2008, ISBN-10: 0-4153-1168-3, ISBN-13: 978-0-4153-1168-7

Last update: McGachy Lenka (03.05.2024)
Learning resources -

https://e-learning.vscht.cz/course/view.php?id=422

Last update: McGachy Lenka (03.05.2024)
Syllabus -

1. Introduction, structure of the subject, history of toxicology, ecotoxicology, concepts and definitions, basics of toxicodynamics and toxicokinetics.

2. Substances versus organism - uptake of substances, barriers, absorption, distribution.

3. Biotransformation of substances, examples of biotransformation reactions of toxic substances. Excretion.

4. Effects of substances, types and mechanisms of effects.

5. Investigation of toxicity, literature sources and experimental procedures.

6. Regulation of work with chemicals and SDS.

7. Toxicity, ecotoxicity and risks of inorganic substances.

8. Toxicity, ecotoxicity and risks of organic substances.

9. Abuse of chemical substances: chemical weapons and addictive substances.

10. Safety in chemical workplaces (main hazards, ways to minimize the risk).

11. Abiotic and biotic parts of the global ecosystem.

12. Biogeochemical cycles and streams of energy in nature.

13. Toxic substances in the environment.

14. Current environmental problems.

Last update: McGachy Lenka (03.05.2024)
Registration requirements -

None

Last update: Kočí Vladimír (10.01.2018)
Course completion requirements -

Written exam

• students enrol in SIS

• the test is set and marked by the course teacher, or a person authorised by the course teacher

• to complete the course students, have to pass written exam with minimum score of 50%

Last update: McGachy Lenka (06.09.2023)
Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na zkoušku a její absolvování 2 56
3 / 3 84 / 84
 
VŠCHT Praha