SubjectsSubjects(version: 863)
Course, academic year 2019/2020
Toxicology and Ecotoxicology I - B240001
Title: Toxikologie a ekotoxikologie I
Guaranteed by: Department of Environmental Chemistry (240)
Actual: from 2019
Semester: both
Points: 3
E-Credits: 3
Examination process:
Hours per week, examination: 2/0 Ex [hours/week]
Capacity: winter:unlimited / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
For type: Bachelor's
Additional information: http://Předmět je vyučován pouze v zimním semestru. Zkoušky se konají u přednášejících.
Old code: ZTOE
Note: you can enroll for the course in winter and in summer semester
Guarantor: Čapek Pavel doc. Ing. CSc.
Kočí Vladimír doc. Ing. Ph.D., MBA
McGachy Lenka Ing. Ph.D.
Interchangeability : N111009, N240011, Z240011
This subject contains the following additional online materials
Annotation -
Last update: Kočí Vladimír doc. Ing. Ph.D., MBA (10.01.2018)
Toxicology deals with the interaction of chemicals and the living organism. It is the subject of a summary of basic information on substances that damage the living organism. The subject acquaints with the fate of the substances in the organism and their effects on them and with the way of their toxicity. Several lectures focus on selected inorganic and organic toxic substances and some of their groups. One lecture introduces the prevention of accidents, principles of safe work with toxic substances, describes firefighting and first aid bases. Other lectures briefly describe the environment, the flow of substances and energy in it. The final lectures follow up on the topic of toxic substances in the environment and the problems associated with them.
Aim of the course -
Last update: Kočí Vladimír doc. Ing. Ph.D., MBA (10.01.2018)

Students will be able to understand:

  • The basic survey about toxicity and negative influence of certain chemical materials on human organism
  • The fate of xenobiotics in organism: entrance, distribution, biotransformation, excretion
  • The safe disposal with chemical substances and principles of first aid during accidents in chemical laboratory
Literature -
Last update: Linhart Igor doc. Ing. CSc. (30.08.2019)

Linhart I.: Basic Terms in Toxicology, Ecology and Ecotoxicology (A bilingual textbook). UCT Press, UCT Prague, 2019, ISBN: 978-80-7592-040-9.


Gilbert Steven G.: A Small Dose of Toxicology, The Health Effects of Common Chemicals, Informa Healthcare USA, 2008, ISBN-10: 0-4153-1168-3, ISBN-13: 978-0-4153-1168-7

Bardoděj Z.: Introduction to Chemical Toxicology, Karolinum, 2000, ISBN: 8071849790

Learning resources -
Last update: Kočí Vladimír doc. Ing. Ph.D., MBA (10.01.2018)

Syllabus -
Last update: Kočí Vladimír doc. Ing. Ph.D., MBA (10.01.2018)

1. Presentation and structure of the subject, history of toxicology, ecotoxicology and ecology, concepts and definitions.

2. Substances versus organism - barriers to entry, substance input, absorption, distribution.

3. Biotransformation of substances, examples of biotransformation reactions of toxic substances.

4. Effects of substances, types and mechanisms of effects.

5. Detection of toxicity, literary sources and experimental procedures.

6. Regulation of work with chemicals and MSDS.

7. Toxicity, ecotoxicity and risks of inorganic substances.

8. Toxicity, ecotoxicity and risks of organic substances.

9. Abuse of chemical substances: combat chemical substances and addictive substances.

10. Safety in chemical workplaces (main risks and ways to minimize them).

11. Abiotic and biotic components of the global ecosystem.

12. Streams of substances and energy in nature.

13. Toxic substances in the environment.

14. Current environmental problematics.

Registration requirements -
Last update: Kočí Vladimír doc. Ing. Ph.D., MBA (10.01.2018)


Course completion requirements -
Last update: Kubová Petra Ing. (09.01.2020)

Examination requirements:

The exam starts with written part (student must get min 50 per cent). After successfull written part the oral exam follows.

Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na zkoušku a její absolvování 2 56
3 / 3 84 / 84
Coursework assessment
Form Significance
Examination test 50
Oral examination 50