SubjectsSubjects(version: 965)
Course, academic year 2024/2025
  
Specialized Laboratory of drug production - M111015
Title: Laboratoř specializace - výroba léčiv
Guaranteed by: Department of Organic Technology (111)
Faculty: Faculty of Chemical Technology
Actual: from 2022
Semester: winter
Points: winter s.:7
E-Credits: winter s.:7
Examination process: winter s.:
Hours per week, examination: winter s.:0/10, MC [HT]
Capacity: unknown / unlimited (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Level:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Školáková Tereza Ing. Ph.D.
Kovanda František prof. Ing. CSc.
Vránová Lenka Ing. Ph.D.
Class: Základní laboratoře
Interchangeability : N111049
This subject contains the following additional online materials
Annotation -
Students pass successively several type works where they learn the basic procedures in the laboratory, which include organic syntheses, analytical methods and separation processes.
Last update: Kubová Petra (04.01.2018)
Course completion requirements - Czech

K udělení zápočtu je nutná aktivní účast na laboratorních pracích, odevzdání laboratorních protokolů a získání z každé práce alespoň klasifikaci "E". Další podmínkou je účast na Zakončení laboratoří.

Last update: Krupka Jiří (20.02.2018)
Literature -

Manuals for laboratory work distributed in the workplace.

Last update: Kubová Petra (04.01.2018)
Syllabus -

1. Introduction to the laboratory. Safety training, fire protection, first aid.

2. Test of dissolution of solid drug forms.

3. Immobilization of the aluminosilicate materials.

4. Using the GC-MS spectrometry.

5. Rectification.

6. The decontamination process using hydrogen peroxide vapor (VPHP process).

7. Etherification of alcohols on acidic heterogeneous catalysts in the gas phase.

8. Solvent effects on the kinetics of the hydrogenation of alkylantraquinones.

9. Evaluation of chromatographic data.

10. Measurement of liquid-vapor equilibrium.

11. Effect of ionic liquids on stereoselective hydrogenation in homogeneous phase for the preparation of optically pure compounds.

12. Influence of hydrogen peroxide concentration on the rate of epoxidation of olefins.

13. The use of instrumental analytical HPLC method for kinetic study of K2PtCl4 aquatation.

14. Working with chemical databases.

15. Measurement of the specific surface area of sorbents.

16. Final evaluation of laboratories with students.

Last update: Kubová Petra (04.01.2018)
Learning resources -

https://uot.vscht.cz/studium/magisterske-studium/66277

Last update: Školáková Tereza (17.07.2023)
Learning outcomes -

Students will be able to:

use basic synthetic, analytical and separation laboratory procedures.

Last update: Kubová Petra (04.01.2018)
Registration requirements -

Organic chemistry I, Analytical chemistry I

Last update: Kubová Petra (04.01.2018)
Teaching methods
Activity Credits Hours
Účast v laboratořích (na exkurzi nebo praxi) 4 112
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1.1 30
Práce na individuálním projektu 1.9 54
7 / 7 196 / 196
 
VŠCHT Praha