SubjectsSubjects(version: 955)
Course, academic year 2023/2024
Environmental Toxicology - M240011
Title: Environmentální toxikologie
Guaranteed by: Department of Environmental Chemistry (240)
Faculty: Faculty of Environmental Technology
Actual: from 2023
Semester: summer
Points: summer s.:3
E-Credits: summer s.:3
Examination process: summer s.:
Hours per week, examination: summer s.:2/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Kočí Vladimír prof. Ing. Ph.D., MBA
McGachy Lenka Ing. Ph.D.
Honzajková Zuzana Ing. Ph.D.
Interchangeability : N240015
This subject contains the following additional online materials
Annotation -
The aim of the course is to understand the effects of environmental pollutants on humans and other organisms. Types and mechanisms of toxic effects and factors influencing these effects, biotransformation, excretion, biodegradation and bioaccumulation of environmental pollutants are explained within the course. The content of the course contains descriptions of the most important groups of environmental pollutants, their sources in the environment, applications and negative effects on living organisms. The course also includes an introduction into Environmental Risk Assessment.
Last update: McGachy Lenka (23.01.2018)
Aim of the course -

Students will be able to:

•Define and explain type and mechanisms of xenobiotic action in organisms, their biotransformation and excretion and processes of xenobiotics biodegradation and


•Describe the toxicity and adverse effects of currently common environmental pollutants on plants and other organisms.

•Assess the potential negative effects and risks to humans arising from exposure to selected pollutant groups.

Last update: McGachy Lenka (23.01.2018)
Literature -

Linhart, I., Toxikologie: Interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky, Vysoká škola chemicko-technologická v Praze, Praha, 2012, 978-80-7080-806-1.

Ming-Ho Yu, Humio Tsunoda, Masashi Tsunoda, Environmental Toxicology: Biological and Health Effects of Pollutants, Third Edition: CRC Press, New York, 2011, ISBN 9781439840382.

Last update: McGachy Lenka (24.01.2018)
Learning resources -

Last update: Kubová Petra (23.02.2018)
Requirements to the exam -

Grading Policy:

Percentage contributions to the final grade are as follows:

Team project (project report, 20%; team project presentation, 20%).

Written exam, 60%.

Team project:

Students will be grouped into teams of 2 students to work jointly on a project to investigatea toxicant for which there is reason to be concerned about possible adverse health effects on the human population.

In the second half of the course, teams must schedule at least one meeting with a teacher to discuss the progress of their project. Failure to hold this meeting will result in a 20% reduction in the project grade.

Written Exam:

To complete the course students, have to pass written exam with minimum score of 50%.

Last update: McGachy Lenka (17.01.2022)
Syllabus -

1) Environmental change and health (our changing environment, global climate changes, air, water and soil pollution, wastes, examples of environmental diseases).

2) Occurrence of toxicants in the environment (adverse effects on plants, animals and humans, acute and chronic toxicity - examples).

3) Toxic action of pollutants on plants and humans (exposure, uptake, transport, type and mechanisms of action).

4) Factors affecting xenobiotic action (pchysicochemical properties, dose and concentration, duration and mode of exposure, interaction, environmental, biological and

nutritional factors).

5) Biotransformation and Excretion, Biodegradation, Bioaccumulation.

6) Air pollution (inorganic gases, particulate matter).

7) Environmental pollutants – Volatile Organic Compounds (Petroleum Hydrocarbons, Polycyclic Aromatic Hydrocarbons, Halogenated hydrocarbons).

8) Environmental pollutants – heavy metals and metalloids.

9) Environmental pollutants – persistent organic pollutants (Insecticide, Herbicide, Polychlorinated Biphenyls, Polybrominated Biphenyls, Dioxins).

10) Endocrine disruptors and residual pharmaceutics.

11) Carcinogenic and mutagenic pollutants.

12) Toxicology of nanomaterials.

13) Ecological Risk Assessment (introduction, use, importance and frameworks for Ecological Risk Assessment, Analysis and Risk characterization).

14) Project presentation and discussion.

Last update: Kubová Petra (23.02.2018)
Registration requirements -


Last update: McGachy Lenka (23.01.2018)
Course completion requirements -

Exam test. Project report and its presentation.

Last update: McGachy Lenka (25.01.2018)
Teaching methods
Activity Credits Hours
Obhajoba individuálního projektu 0.5 14
Účast na přednáškách 1 28
Práce na individuálním projektu 0.5 14
Příprava na zkoušku a její absolvování 1 28
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