SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Chemistry of Natural Compounds - M342004
Title: Chemie přírodních látek
Guaranteed by: Department of Chemistry of Natural Compounds (342)
Actual: from 2019
Semester: winter
Points: winter s.:3
E-Credits: winter s.:3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0 Ex [hours/week]
Capacity: unlimited / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
For type: Master's (post-Bachelor)
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Staněk Jan doc. RNDr. CSc.
Interchangeability : N342006
Annotation -
Last update: Kubová Petra Ing. (19.12.2017)
The course introduces the basic, structurally derived groups of natural compounds, their properties, reactions and occurrence in organism. It explains also basic concepts relating to structure of molecules, their stereochemistry and/or chirality, including structure-biological activity relationships, e.g. for narcotics. The course deals also with enzymatic and biomimetic reactions.
Aim of the course -
Last update: Kubová Petra Ing. (19.12.2017)

Students will be able to:

Classify natural compounds into individual structural classes

Describe structure, properties and reactions of individual classes of natural compounds and their biogenesis

Assess structure-reactivity relationships

Depict reaction mechanisms of basic reaction types

Literature -
Last update: Kubová Petra Ing. (19.12.2017)

R: McMurry J.: Organic chemistry, 8th Ed., Brooks/Cole, Cengage Learning, 2012, 9780840054449

Learning resources -
Last update: Kubová Petra Ing. (19.12.2017)

Lecture notes

Syllabus -
Last update: Kubová Petra Ing. (19.12.2017)

1. Definition of natural compounds and products

2. Stereochemistry of natural compounds

3. Structure-biogenesis relationships, metabolic pathways determination

4. Natural compounds derived from acetate

5. Saturated and unsaturated fatty acids and prostaglandins

6. Polyketides and their cyclization

7. Deoxysaccharides, aflatoxins, antibiotics

8. Natural compounds derived from mevalonate

9. Natural products derived from shikimate

10. Natural products derived from amino acids

11. Reactions with coenzymes and their mechanisms

12. Reduction, oxidation

13. Narcotics and their effects, legislation, placebo effect

14. Biomimetic reactions

Registration requirements -
Last update: Kubová Petra Ing. (19.12.2017)

Organic chemistry I

Organic chemistry II or Bioorganic chemistry of natural compounds

Coursework assessment
Form Significance
Regular attendance 20
Oral examination 80

 
VŠCHT Praha