SubjectsSubjects(version: 850)
Course, academic year 2019/2020
  
Drug design - M402020
Title in English: Návrh léčiv
Guaranteed by: Department of Analytical Chemistry (402)
Actual: from 2019
Semester: winter
Points: winter s.:3
E-Credits: winter s.:3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0 Ex [hours/week]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
Is provided by: N402056
For type:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Sýkora David doc. Dr. RNDr.
Interchangeability : N402056
Annotation -
Last update: Pátková Vlasta (05.01.2018)
The search for new pharmaceuticals using knowledge of biological objectives is a complex matter. This course is focused on the chemical nature of this problem.
Aim of the course -
Last update: Pátková Vlasta (05.01.2018)

Students will be able to apply a variety of techniques to address the problems associated with the emergence of new medicines.

Literature -
Last update: Pátková Vlasta (05.01.2018)

R: http://www.vscht.cz/kot/cz/studijni-materialy.html

R: http://www.alga.cz/users/tichym/AMB/12_drugdiscovery.ppt

R: http://www.cc.nih.gov/training/training/principles/slides/DrugDevProgram08-09oneslide.pdf

A: http://mediaserver.aapspharmaceutica.com/meetings/DDS/Integration%20of%20In%20Silico%20Models%20in%20Drug%20Design.pdf

A: http://pharm.swu.ac.th/web_npec/content/JOURNAL/LectureAutoDock.pdf

A: http://www.cc.nih.gov/training/training/principles/slides/DrugDevProgram08-09oneslide.pdf

Learning resources -
Last update: Pátková Vlasta (05.01.2018)

http://www.vscht.cz/kot/cz/studijni-materialy.html

Syllabus -
Last update: Pátková Vlasta (05.01.2018)

1.The identification of biological target.

2.The targeting of drugs on proteins.

3.The targeting of drugs on DNA.

4.Other biological targets.

5.Drug Design: computational methods.

6.Molecular modeling, Docking.

7.Design of anti-cancer agents by function and target biological structure.

8.Cytostatics.

9.Design of anti-virals.

10.Antivirals I.

11.To provide drugs for CNS.

12.To provide drugs for CVS.

13.Natural substances such as structural elements for modern pharmaceuticals I.

14.Natural substances such as structural elements for modern pharmaceuticals II.

Registration requirements -
Last update: Pátková Vlasta (05.01.2018)

None.

Course completion requirements - Czech
Last update: Vosmanská Magda Ing. CSc. (21.02.2018)

Zkouška probíhá formou písemné i ústní zkoušky.

Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 0,3 8
Příprava na zkoušku a její absolvování 1,7 48
3 / 3 84 / 84
Coursework assessment
Form Significance
Regular attendance 20
Examination test 40
Oral examination 40

 
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