SubjectsSubjects(version: 947)
Course, academic year 2023/2024
Clinical Biochemistry in Human Medicine - N320098
Title: Klinická biochemie v humánní medicíně
Guaranteed by: Department of Biochemistry and Microbiology (320)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2021
Semester: winter
Points: winter s.:3
E-Credits: winter s.:3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Is provided by: M320029
For type:  
Guarantor: Fusek Martin prof. Ing. CSc.
Examination dates   Schedule   
Annotation -
Last update: SMIDOVAL (27.03.2015)
During the lectures Clinical biochemistry in human medicine will students learn the major methods of clinical biochemistry focused on novel approaches. Students will also learn the main molecules which are used for the diagnostics of particular diseases and then the relationships between pathological processes and their diagnostics in selected organs will be mentioned.
Aim of the course -
Last update: SMIDOVAL (27.03.2015)
  • Methodical principles used in human diagnostics
  • Overview of the most important analyzed molecules connected to human medicine
  • Relationship between levels of these molecules and the disease and/or cure

Literature -
Last update: SMIDOVAL (27.03.2015)

Z: Novák F., Úvod do klinické biochemie, Karolinum, 2002, 8024603667

D: Zima T., Laboratorní diagnostika, Galén, 2007, 9788024614236

Learning resources -
Last update: SMIDOVAL (27.03.2015)

electronic version of the materials will be sent to students at the start of the term

Syllabus -
Last update: SMIDOVAL (27.03.2015)

1. Introduction

The field of clinical biochemistry and the relationship with diseases

2. Methods in clinical biochemistry

Basic methods

3. Analytical methods - second part


4. Disorders in the metabolism of amino-acids

Main correlation between levels of amino-acids and diseases

5. Proteins and clinical biochemistry

Main studied serum proteins

6. Enzymes - functions and disorders

Correlation between main enzymes and diseases

7. Metabolism of sugars and its disorders

Diabetes and level of glucose and related diagnostics

8. Lipids and metabolism

Levels of particular lipids and correlation to pathology

9. Liver functions and biochemical markers

Diseases of liver and the correlation in the organism

10. Kidney functions and biochemical markers

Diseases of kidneys and the correlation in the organism

11. Hormones and analysis

Main hormones and their relationship to diseases

12. Tumor markers

Significance of tumor markers for the cancer diagnostics

13. Electrolytes

The main ionts of human liquids

14. Acido-basic balance

Regulation of pH and pathological statuses

Registration requirements -
Last update: SMIDOVAL (27.03.2015)

Biochemistry I (N320001) or Biochemistry (D320001) nebo Biochemistry A/B (N320024/N320066)