SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Structure and Reactivity - N342003
Title: Struktura a reaktivita
Guaranteed by: Department of Chemistry of Natural Compounds (342)
Actual: from 2013
Semester: summer
Points: summer s.:4
E-Credits: summer s.:4
Examination process: summer s.:
Hours per week, examination: summer s.:2/1 C+Ex [hours/week]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
For type:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Parkan Kamil Ing. Ph.D.
Is interchangeable with: M342002
Examination dates   Schedule   
Annotation -
Last update: TAJ342 (18.12.2013)
The subject is aimed at understanding basic principles and mechanisms in modern organic chemistry. Attention is given primarily to the structure of organic compounds and their reactivity which is a prerequisite for a deeper understanding of organic chemistry.
Aim of the course -
Last update: TAJ342 (27.09.2013)

Students will be able to:

Understand the basics of molecular structure (AO, MO) and structure of organic compounds (isomers)

Assess reactivity of organic compounds (thermodynamics, kinetics)

Depict reaction mechanisms of principle organic reactions (nucleophilic substitution, addition, elimination, …)

Literature -
Last update: TAJ342 (27.09.2013)

R: Mark G. Moloney: Structure and Reactivity in Organic Chemisty, Wiley-Blackwell, 2008, 978-1405114516

A: McMurry J.: Organic chemistry, 8th Ed., Brooks/Cole, Cengage Learning, 2012, 9780840054449

Learning resources -
Last update: TAJ342 (29.09.2013)

Lecture notes

Syllabus -
Last update: TAJ342 (29.09.2013)

1. Valency (structure, covalent bond)

2. Structure (configuration, conformation)

3. Reactivity (thermodynamics, kinetics, …)

4. Intermediates (carbocations, carbanions, radicals, carbenes, benzynes, ketenes)

5. Acids and bases (Lowry-Brønsted theory)

6. Nucleophilic substitution (SN1 reaction, SN2 reaction, synthetic applications)

7. Addition reactions (AE, AN, addition of ketenes, synthetic applications)

8. Elimination reactions (elimination, oxidation processes, …)

9. Aromatic substitution (aromaticity, reactions)

10. Stepwise addition and elimination reactions (addition-elimination reaction, metathesis, …)

11. Radical reactions (radical generation, subsequent reactions)

12. Coupling reactions (Pd-catalyzed reactions, reactions catalyzed by other elements)

13. Pericyclic reactions (molecular orbitals, pericyclic reactions, synthetic applications)

14. Types of non-covalent bonds (hydrogen bond in bioorganic molecules, …)

Registration requirements -
Last update: TAJ342 (29.09.2013)

R: Mark G. Moloney: Structure and Reactivity in Organic Chemisty, Wiley-Blackwell, 2008, 978-1405114516

Course completion requirements
Last update: TAJ342 (27.09.2013)

R: Mark G. Moloney: Structure and Reactivity in Organic Chemisty, Wiley-Blackwell, 2008, 978-1405114516

A: McMurry J.: Organic chemistry, 8th Ed., Brooks/Cole, Cengage Learning, 2012, 9780840054449

Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0,5 14
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 0,5 14
Práce na individuálním projektu 0,5 14
Příprava na zkoušku a její absolvování 1 28
Účast na seminářích 0,5 14
4 / 4 112 / 112
Coursework assessment
Form Significance
Regular attendance 20
Defense of an individual project 10
Examination test 25
Continuous assessment of study performance and course -credit tests 20
Oral examination 25

 
VŠCHT Praha