SubjectsSubjects(version: 928)
Course, academic year 2022/2023
Engineering in Chemical and Pharmaceutical Processes - S111048
Title: Engineering in Chemical and Pharmaceutical Processes
Guaranteed by: Department of Organic Technology (111)
Faculty: Faculty of Chemical Technology
Actual: from 2019
Semester: winter
Points: winter s.:6
E-Credits: winter s.:6
Examination process: winter s.:
Hours per week, examination: winter s.:3/1, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: English
Teaching methods: full-time
Is provided by: AM111014
For type:  
Additional information:
Guarantor: Zámostný Petr prof. Ing. Ph.D.
Interchangeability : N111048
Is interchangeable with: N111048
Examination dates   Schedule   
Last update: Zámostný Petr prof. Ing. Ph.D. (06.08.2018)
Chemical and Pharmaceutical Process Engineering course is aimed at providing the understanding of the unit operations employed in the pharmaceutical industry, in the chemical part of API synthesis, as well as in the dosage form manufacturing. Operations or their aspects that are beyond the scope of general chemical engineering courses constitute the essential part of this course. The understanding of the unit operations and process principles is supported by substantial amount of insight into properties of particulate solids, considering their key role in contemporary solid dosage forms design and manufacturing, and also by introductory course into the process control and safety.
Aim of the course
Last update: Zámostný Petr prof. Ing. Ph.D. (06.08.2018)

Students will be able to:

Analyze and optimize basic processes in chemical and pharmaceutical industry

Create protocols and operating sheets compliant with the industrial standards

Design suitable approach for scaling up the process from laboratory to production scale

Last update: Zámostný Petr prof. Ing. Ph.D. (06.08.2018)

R:Rhodes M.,Introduction to Particle Technology,Wiley,New York,2008,0471984833

R:Hickey A.J.,Pharmaceutical Process Engineering,M.Dekker,2001,0824702980

A:Levin M.,Pharmaceutical process scale up,M.Dekker,2002,0824706250

A:Klefenz H.,Industrial Pharmaceutical Biotechnology,Wiley,N.Y.,2002,3527299955

A:Fogler H.S.,Elements of Reaction Engineering,Prentice,Hall,New Jersey,2000,0130473944

Learning resources
Last update: Zámostný Petr prof. Ing. Ph.D. (07.08.2018)

Public available older version

New materials are available on UCT E-learning system

Last update: Zámostný Petr prof. Ing. Ph.D. (07.08.2018)

1. Characteristics and characterization of particles and particulate systems

2. Particle size reduction and classification

3. Introduction to mechanics of particulate solids

4. Particle agglomeration processes, high-shear, and fluidized-bed granulation

5. Compaction processes

6. Extrusion and postprocessing of agglomerated products

7. Tablet compression

8. Mixing and segregation in particulate systems

9. Pharmaceutical processes scale up, general scale up considerations

10. Fluid flow and transport in pharma applications

11. Processes involving particulate solid interaction with liquids

12. Applied reaction kinetics

13. Reaction kinetics of biotechnological processes

14. Introduction to process control, safety considerations in chemical and pharmaceutical processes

Registration requirements
Last update: Zámostný Petr prof. Ing. Ph.D. (07.08.2018)

Mathematics I, Unit Operations of Chemical Engineering I