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Reactions based on the chemistry of transition metals play an important role both in the chemical industry and in the organic synthesis. This course is divided into two parts. In the first part the students familiarize themselves with basic principles of the chemistry of transition metals, with the reactions in coordination sphere and with chemical properties of common ligands. The second part deals with an application of this chemistry in some important industrial processes and especially in the organic synthesis. Poslední úprava: Tobrman Tomáš (12.05.2026)
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Successful passing of two seminar tests and oral exam. Poslední úprava: Tobrman Tomáš (12.05.2026)
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1. Formalism (oxidation state, d-electron configuration, 18-electron rule). 2. Basic types of ligands (s-complexes). 3. Basic types of ligands (p-complexes). 4. Reactions in coordination sphere of transition metals (ligand substitution, oxidative addition, reductive elimination, insertion, transmetallation). 5. Nucleophilic attack on ligands coordinated to transition metals. 6. Electrophilic attack on ligands coordinated to transition metals. 7. Homogeneous catalytic reactions (hydrogenation, hydrosilation, hydrocyanation, alkene and alkyne polymerisation, carbonylation reactions). 8. Synthetic applications of transition metal hydrides, organocuprates. 9. Synthetic applications of complexes from insertion of alkenes and alkynes. 10. Synthetic applications of complexes from oxidative addition followed with insertion of alkene, alkyne and carbon monoxide (cross coupling, Heck reaction). 11. Synthetic applications of transition metal carbonyl complexes. 12. Synthetic applications of transition metal carbene complexes (reactions of nucleophilic and electrophilic carbenes, alkene metathesis, metal-catalysed decomposition of diazo compounds). 13. Synthetic applications of h3-allyl transition metal complexes. 14. Synthetic applications of transition metal h6-arene complexes (Cr(CO)3 and FeCp+ complexes). Poslední úprava: Tobrman Tomáš (12.05.2026)
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Organic Synthesis, Organic Reaction Mechanisms Poslední úprava: Tobrman Tomáš (12.05.2026)
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| Zátěž studenta | ||||
| Činnost | Kredity | Hodiny | ||
| Účast na přednáškách | 1.5 | 42 | ||
| Příprava na zkoušku a její absolvování | 4 | 112 | ||
| Účast na seminářích | 0.5 | 14 | ||
| 6 / 6 | 168 / 168 | |||