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Last update: Hladíková Jana (12.12.2017)
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Last update: Hladíková Jana (12.12.2017)
Students will be able to: characterize important groups or individual compounds produced by secondary metabolism; describe the important metabolic pathways for the synthesis of secondary metabolites and their regulation; propose application of the most important secondary metabolites; recognize the risks associated with the mechanism and evolution of resistance to secondary metabolites such as used in medicine, food, etc. |
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Last update: Masák Jan prof. Ing. CSc. (12.09.2023)
R:Rehm,H.-J.,Reed G.: Biotechnology: Products of Secondary Metabolism, Vol 7, 2nd Ed, Wiley, Weinheim, 2008, 9783527620890 A:Cole,R.J.: Handbook of Secondary Fungal Metabolites, Elsevier, New York,2003, 978012179606 R:Carocho, M., Heleno, S.M., Barros, L.: Natural Secondary Metabolites, Springer, Cham 2023, 2006, 9783031185861 |
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Last update: Masák Jan prof. Ing. CSc. (03.02.2018)
https://e-learning.vscht.cz/ |
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Last update: Masák Jan prof. Ing. CSc. (03.02.2018)
Preparation and defense of the seminar paper. |
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Last update: Hladíková Jana (12.12.2017)
1. Introduction - definitions of "secondary metabolism", "secondary metabolite" 2. Origin, evolution and genetic determination of secondary metabolism 3. Distribution and function of secondary metabolism in living organisms 4. List of important metabolic pathways of secondary metabolism and their regulation 5. Overview of the biological activities of secondary metabolites 6. Secondary metabolism in microorganisms 7. Antimicrobial compounds 8. Secondary metabolites with cancerostatic activity 9. Microbial toxins 10. Microbial alkaloids and growth modulators 11. Secondary metabolites produced by plants I 12. Secondary metabolites produced by plants II 13. Resistance mechanisms against the toxic effects of secondary metabolites 14. Current trends in research and application of secondary metabolites |
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Last update: Hladíková Jana (12.12.2017)
Biochemistry, Microbiology, Organic chemistry |
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Last update: Masák Jan prof. Ing. CSc. (03.02.2018)
Course credit based on the presentation of the seminar paper. Oral exam. |
Teaching methods | ||||
Activity | Credits | Hours | ||
Účast na přednáškách | 1 | 28 | ||
Práce na individuálním projektu | 1 | 28 | ||
Příprava na zkoušku a její absolvování | 2 | 56 | ||
4 / 4 | 112 / 112 |