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Last update: Hladíková Jana (20.12.2017)
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Last update: Hladíková Jana (20.12.2017)
Students will be able to: Understand the biological, chemical and engineering processes in the biotechnology industry Describe and evaluate basic biocatalytic processes. Quantitatively evaluate experimental data of processes catalyzed by biological elements and to carry out heat and mass balances of biotechnological processes. Design mixing and aeration equipment of bioreactors. |
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Last update: Hladíková Jana (20.12.2017)
R: Doran P.M.: Bioprocess Engineering Principles, Academic, London, 1995, ISBN: 9780122208553 R: Moo-Young M.: Comprehensive biotechnology, Elsevier B.V., 2011, ISBN: 9780080885049 A: Dunn I.J. et al.: Biological Reaction Engineering, Wiley-VCH, 2003, ISBN:9783527307593 A: Najafpour G.D.: Biochemical Engineering and Biotechnology, Elsevier B.V., 2007, ISBN 9780444528452 |
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Last update: Brányik Tomáš prof. Ing. Ph.D. (23.01.2018)
https://e-learning.vscht.cz/course/view.php?id=455 |
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Last update: Hladíková Jana (20.12.2017)
1. The issue of biotechnology and bioengineering. 2. The structure of bioprocess, equipment overview and unit operations. 3. Methods of optimization and modeling of biological processes. 4. Engineering kinetics of chemical and enzymatic reactions, kinetics of microbial growth. 5. Cultivation of microorganisms - batch and fed-batch cell cultures. 6. Cultivation of microorganisms - semicontinuous and continuous cell cultures. 7. Characteristics of phase folw - residence time distribution, flow models. 8. Mass transfer - oxygen transfer, aeration, measurement and quantification of KLa. 9. Specific aspects of plant/tissue cell and phototrophic cell cultivation. 10. Engineering aspects of enzyme and cell immobilization, biocatalysis. 11. Mixing in bioreactors - theory, power consumption, homogenization, shear forces. 12. Heat transfer, energy balance of bioreactors, sterilization, cooling and heating. 13. Scale-up of bioprocesses. 14. Construction materials, corrosion, design and construction of biotechnological processes. |
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Last update: Kubová Petra Ing. (04.02.2020)
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Last update: Brányik Tomáš prof. Ing. Ph.D. (23.01.2018)
Credit test (rated at least 50%). Exam test (rated at least 50%). Oral exam. |
Teaching methods | ||||
Activity | Credits | Hours | ||
Konzultace s vyučujícími | 0.2 | 6 | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi | 0.5 | 14 | ||
Příprava na zkoušku a její absolvování | 1.8 | 50 | ||
Účast na seminářích | 0.5 | 14 | ||
4 / 4 | 112 / 112 |
Coursework assessment | |
Form | Significance |
Regular attendance | 10 |
Examination test | 30 |
Oral examination | 60 |