SubjectsSubjects(version: 916)
Course, academic year 2019/2020
Bioengineering II - M319005
Title: Bioinženýrství II
Guaranteed by: Department of Biotechnology (319)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2019
Semester: summer
Points: summer s.:4
E-Credits: summer s.:4
Examination process: summer s.:
Hours per week, examination: summer s.:3/0, Ex [HT]
Capacity: unlimited / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
For type: Master's (post-Bachelor)
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Páca Jan prof. Ing. DrSc.
Interchangeability : N319016
Examination dates   Schedule   
This subject contains the following additional online materials
Annotation -
Last update: Hladíková Jana (20.12.2017)
The course focuses on understanding biological processes and their applications in unit operations of biotechnological production. It is based on a quantitative description of formation, preservation and transformation of energy in cells during cell growth and product formation. Building on the knowledge of Bioengineering I, the course develops deeper understanding of the relationships between processes, and the ability to select the appropriate types of equipment and carry out their design into a production line.
Aim of the course -
Last update: Hladíková Jana (20.12.2017)

Students will be able to:

Analyze and optimize cultivation processes in the biotechnology industry.

Evaluate the quantity of heat released during cell cultivation.

Design a suitable production process and select machinery for production lines.

Literature -
Last update: Hladíková Jana (20.12.2017)

R: Doran P.M.: Bioprocess Engineering Principles, Academic, London, 1995, ISBN: 9780122208553

R: Moo-Young M.: Comprehensive biotechnology, Elsevier B.V., 2011, ISBN: 9780080885049

A: Dunn I.J. et al.: Biological Reaction Engineering, Wiley-VCH, 2003, ISBN:9783527307593

A: Najafpour G.D.: Biochemical Engineering and Biotechnology, Elsevier B.V., 2007, ISBN 9780444528452

Learning resources -
Last update: Hladíková Jana (20.12.2017)

Syllabus -
Last update: Hladíková Jana (20.12.2017)

1. Formation and transfer of energy in cell - basic principles

2. Coupling of reactions and reaction systems. Maintenance energy and endogenous metabolism.

3. Differences in cell energetics in terms of transport pathway, and the final electron acceptor

4. Transformation, transduction, and energy conservation in cell and product formation.

5. Energy coupling during cell growth and product formation.

6. Regulating of sub-metabolic systems.

7. Heat generation during microbial process. Heat balance of bioreactor.

8. Bioreactors with mechanical agitation - types, models and applications.

9. Bioreactors with pneumatic and hydraulic agitation - types, models and applications.

10. Special bioreactors for cultivation of microbial, plant, and tissue cells.

11. Measurement and control of bioreactors. Design elements.

12. Preparatory operations and equipment in biotechnolology.

13. Downstream operations and equipment in biotechnolology

14. Special processes, equipment and their practical applications. Examples of biotechnological production.

Registration requirements -
Last update: Hladíková Jana (20.12.2017)

Bioengineering I


Chemical engineering

Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0,2 6
Obhajoba individuálního projektu 0,1 3
Účast na přednáškách 1,5 42
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Práce na individuálním projektu 0,4 11
Příprava na zkoušku a její absolvování 0,8 22
4 / 4 112 / 112
Coursework assessment
Form Significance
Regular attendance 10
Report from individual projects 10
Examination test 20
Oral examination 60