SubjectsSubjects(version: 949)
Course, academic year 2019/2020
Bioengineering II - N319016
Title: Bioinženýrství II
Guaranteed by: Department of Biotechnology (319)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2019 to 2020
Semester: summer
Points: summer s.:5
E-Credits: summer s.:5
Examination process: summer s.:
Hours per week, examination: summer s.:3/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Is provided by: M319005
For type:  
Guarantor: Páca Jan prof. Ing. DrSc.
Is interchangeable with: M319005
Examination dates   Schedule   
Annotation -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)
The course focuses on understanding biological processes and their applications in unit operations of biotechnological production. It is based on a quantitative description of formation, preservation and transformation of energy in cells during cell growth and product formation. Building on the knowledge of Bioengineering I, the course develops deeper understanding of the relationships between processes, and the ability to select the appropriate types of equipment and carry out their design into a production line.
Aim of the course -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)

Students will be able to:

Analyze and optimize cultivation processes in the biotechnology industry.

Evaluate the quantity of heat released during cell cultivation.

Design a suitable production process and select machinery for production lines.

Literature -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)

R: Doran P.M.: Bioprocess Engineering Principles, Academic, London, 1995, ISBN: 9780122208553

R: Moo-Young M.: Comprehensive biotechnology, Elsevier B.V., 2011, ISBN: 9780080885049

A: Dunn I.J. et al.: Biological Reaction Engineering, Wiley-VCH, 2003, ISBN:9783527307593

A: Najafpour G.D.: Biochemical Engineering and Biotechnology, Elsevier B.V., 2007, ISBN 9780444528452

Learning resources -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)

Syllabus -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)

1. Formation and transfer of energy in cell - basic principles

2. Coupling of reactions and reaction systems. Maintenance energy and endogenous metabolism.

3. Differences in cell energetics in terms of transport pathway, and the final electron acceptor

4. Transformation, transduction, and energy conservation in cell and product formation.

5. Energy coupling during cell growth and product formation.

6. Regulating of sub-metabolic systems.

7. Heat generation during microbial process. Heat balance of bioreactor.

8. Bioreactors with mechanical agitation - types, models and applications.

9. Bioreactors with pneumatic and hydraulic agitation - types, models and applications.

10. Special bioreactors for cultivation of microbial, plant, and tissue cells.

11. Measurement and control of bioreactors. Design elements.

12. Preparatory operations and equipment in biotechnolology.

13. Downstream operations and equipment in biotechnolology

14. Special processes, equipment and their practical applications. Examples of biotechnological production.

Registration requirements -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)

Bioengineering I


Chemical engineering

Course completion requirements -
Last update: Páca Jan prof. Ing. DrSc. (30.01.2018)

Test and oral exam

Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0.2 6
Obhajoba individuálního projektu 0.1 3
Účast na přednáškách 1.5 42
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Práce na individuálním projektu 0.4 11
Příprava na zkoušku a její absolvování 1.8 50
5 / 5 140 / 140
Coursework assessment
Form Significance
Regular attendance 10
Report from individual projects 10
Examination test 20
Oral examination 60