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Last update: TAJ319 (10.12.2013)
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Last update: TAJ319 (10.12.2013)
Students will be able to: characterize important groups or individual compounds produced by secondary metabolism; describe the important metabolic pathways for the synthesis of secondary metabolites and their regulation; propose application of the most important secondary metabolites; recognize the risks associated with the mechanism and evolution of resistance to secondary metabolites such as used in medicine, food, etc. |
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Last update: TAJ319 (30.08.2013)
R:Rehm,H.-J.,Reed G.: Biotechnology: Products of Secondary Metabolism, Vol 7, 2nd Ed, Wiley, Weinheim, 2008, 9783527620890 A:Cole,R.J.: Handbook of Secondary Fungal Metabolites, Elsevier, New York,2003, 978012179606 A:Crozier,A:Plant Secondary Metabolites: Occurrence, Structure and Role in the Human Diet,Wiley, Oxford, 2006, 978145125093 |
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Last update: Masák Jan prof. Ing. CSc. (30.08.2013)
http://eso.vscht.cz/ |
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Last update: Masák Jan prof. Ing. CSc. (30.08.2013)
1. Introduction - definitions of "secondary metabolism", "secondary metabolite" 2. Origin, evolution and genetic determination of secondary metabolism 3. Distribution and function of secondary metabolism in living organisms 4. List of important metabolic pathways of secondary metabolism and their regulation 5. Overview of the biological activities of secondary metabolites 6. Secondary metabolism in microorganisms 7. Antimicrobial compounds 8. Secondary metabolites with cancerostatic activity 9. Microbial toxins 10. Microbial alkaloids and growth modulators 11. Secondary metabolites produced by plants I 12. Secondary metabolites produced by plants II 13. Resistance mechanisms against the toxic effects of secondary metabolites 14. Current trends in research and application of secondary metabolites |
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Last update: Masák Jan prof. Ing. CSc. (30.08.2013)
Biochemistry, Microbiology, Organic chemistry |
Teaching methods | ||||
Activity | Credits | Hours | ||
Konzultace s vyučujícími | 0.5 | 14 | ||
Účast na přednáškách | 1 | 28 | ||
Práce na individuálním projektu | 1 | 28 | ||
Příprava na zkoušku a její absolvování | 1 | 28 | ||
Účast na seminářích | 0.5 | 14 | ||
4 / 4 | 112 / 112 |
Coursework assessment | |
Form | Significance |
Regular attendance | 30 |
Defense of an individual project | 30 |
Oral examination | 40 |