Drug design - N402056
Title: Návrh léčiv
Guaranteed by: Department of Analytical Chemistry (402)
Faculty: Faculty of Chemical Engineering
Actual: from 2020
Semester: winter
Points: winter s.:5
E-Credits: winter s.:5
Examination process: winter s.:
Hours per week, examination: winter s.:3/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: cancelled
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Sýkora David prof. Dr. RNDr.
Is interchangeable with: M402020
Examination dates   Schedule   
Annotation -
The search for new pharmaceuticals using knowledge of biological objectives is a complex matter. This course is focused on the chemical nature of this problem.
Last update: VED402 (01.10.2013)
Aim of the course -

Students will be able to apply a variety of techniques to address the problems associated with the emergence of new medicines.

Last update: VED402 (01.10.2013)
Literature -

R: http://www.vscht.cz/kot/cz/studijni-materialy.html

R: http://www.alga.cz/users/tichym/AMB/12_drugdiscovery.ppt

R: http://www.cc.nih.gov/training/training/principles/slides/DrugDevProgram08-09oneslide.pdf

A: http://mediaserver.aapspharmaceutica.com/meetings/DDS/Integration%20of%20In%20Silico%20Models%20in%20Drug%20Design.pdf

A: http://pharm.swu.ac.th/web_npec/content/JOURNAL/LectureAutoDock.pdf

A: http://www.cc.nih.gov/training/training/principles/slides/DrugDevProgram08-09oneslide.pdf

Last update: VED402 (03.10.2013)
Learning resources -


Last update: VED402 (30.09.2013)
Syllabus -

1.The identification of biological target.

2.The targeting of drugs on proteins.

3.The targeting of drugs on DNA.

4.Other biological targets.

5.Drug Design: computational methods.

6.Molecular modeling, Docking.

7.Design of anti-cancer agents by function and target biological structure.


9.Design of anti-virals.

10.Antivirals I.

11.To provide drugs for CNS.

12.To provide drugs for CVS.

13.Natural substances such as structural elements for modern pharmaceuticals I.

14.Natural substances such as structural elements for modern pharmaceuticals II.

Last update: VED402 (30.09.2013)
Registration requirements -


Last update: VED402 (30.09.2013)
Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1.5 42
Příprava na zkoušku a její absolvování 2.5 70
5 / 5 140 / 140
Coursework assessment
Form Significance
Regular attendance 20
Examination test 80