SubjectsSubjects(version: 955)
Course, academic year 2023/2024
Bioengineering Methods - N409057
Title: Bioinženýrské metody
Guaranteed by: Department of Chemical Engineering (409)
Faculty: Faculty of Chemical Engineering
Actual: from 2021
Semester: winter
Points: winter s.:4
E-Credits: winter s.:4
Examination process: winter s.:
Hours per week, examination: winter s.:2/1, C+Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: cancelled
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Is provided by: M409010
Guarantor: Schreiber Igor prof. Ing. CSc.
Hasal Pavel prof. Ing. CSc.
Is interchangeable with: M409010, AM409010
Examination dates   Schedule   
Annotation -
The course is building on the basic knowledge of chemical engineering by the student and develops applications in bioengineering. Basic approaches including mass and energy balances, transport processes and reaction kinetics are synthesized to provide quantitative description of processes used in bioengineering. Special attention is given to reaction-transport processes in enzyme reactors and reactors with living cultures of microorganisms.
Last update: Schreiber Igor (27.09.2013)
Aim of the course -

Students will be able to:

apply quantitative approaches of chemical engineering to biosystems

design basic types of enzyme reactors and bioreactors

design suitable unit operations for modification of inlets and outles from the bioreactor

Last update: Schreiber Igor (27.09.2013)
Literature -

R: Shuler M. L., Kargi F., Bioprocess Engineering. Basic Concepts, Prentice Hall, Upper Saddle River, 2002, 0-13-081908-5

A: Blanch H. W., Clark D. S., Biochemical Engineering,CRC Taylor and Francis, Boca Raton, 1997, 0-8247-0099-6

Last update: Fialová Jana (26.09.2013)
Learning resources -

lecture notes available at

Last update: Schreiber Igor (27.09.2013)
Syllabus -

1. Enzyme catalysis, thermodynamics of enzyme reactions, limitin cases

2. Enzyme reactors, mathematical models and their analysis

3. Immobilized enzymes, effects of mass transport

4. Effectiveness factor, Damköhler number, analysis of heterogeneous enz. systems

5. Microbial growth, stoichiometry of growth, product formation

6. Growth in batch systems

7. Growth in continual systems

8. Structured vs unstructured models of growth

9. Construction and operation of some fermentor types

10. Stirring and aeration

11. Mixed microbial cultures and their interaction

12. Chemostat dynamics with mixed cultures

13. Operating conditions, scale-up

14. Metabolic engineering, metabolic networks

Last update: Schreiber Igor (27.09.2013)
Registration requirements -

Unit operations of chemical engineering I and II

Last update: Schreiber Igor (06.09.2013)
Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1.5 42
Příprava na zkoušku a její absolvování 1 28
Účast na seminářích 0.5 14
4 / 4 112 / 112
Coursework assessment
Form Significance
Continuous assessment of study performance and course -credit tests 50
Oral examination 50