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Last update: Kubová Petra Ing. (23.05.2016)
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Last update: Kubová Petra Ing. (23.05.2016)
Students will know: Basic principles of molecular genetics and the relationship of their structure and function. Principles of regulation of transfer of genetic information and its variability due to mutations and recombination Mechanisms involved in mutation repair. Basic processes of gene expression as regulation of transcription, in prokaryotes and eukaryotes and posttranscriptional modifications of eukaryotic mRNA, regulation of stability of mRNA and translation, role of small RNAs. Basic principles of work with DNA, methods of DNA analysis and basic applications of polymerase chain reaction |
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Last update: Kubová Petra Ing. (23.05.2016)
R: Lodish, H.; et al. Molecular cell biology, 6th ed.;W.H.Freeman & Co Ltd, 2008. R: Albrets B; et al. Molecular biology of the cell, 5th ed. Garland Science, 2008. R: Clark D.P. Molecular biology, Elsevier Inc., 2005. R: Hitler J.M. Forensic DNA Typing, 2nd ed. Elsevier 2005. |
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Last update: Kubová Petra Ing. (23.05.2016)
none |
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Last update: Kubová Petra Ing. (23.05.2016)
1. Historic overview and basic genetic laws and terms. 2. Structure and function of nucleic acids, genome organization 3. Replication, DNA polymerases, replisome complex. 4. Mutations and repair mechanisms. 5. Recombination, mitotic and meiotic gene segregation, transposition. 6. Regulation of transcription. 7. Posttranscriptional modifications of RNA. 8. Regulatory role of RNA. 9. Translation, posttranslational modifications. 10. Principles of work with DNA and RNA. 11. Methods of analysis of DNA sequence, genome mapping. 12. Labeling of nucleic acids, application of probes. 13. Polymerase chain reaction and its applications. 14. DNA databases. |
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Last update: Kubová Petra Ing. (23.05.2016)
To enroll in the course it is required enrollment in courses N110004 A N320004 |
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Last update: Kubová Petra Ing. (23.05.2016)
Biochemistry I |