Students will be able to:

• apply chemical engineering methods to biological processes, i.e., make use of balances and kinetic equations,

• describe kinetics of biochemical reactions and of biomass and microbial product formation,

• describe quantitatively and design simple bioreactors - stirred batch bioreactor andchemostat.

Z: Shuler M. L., Kargi F., Bioprocess Engineering. Basic Concepts, Prentice Hall, Upper Saddle River, 2002, 0-13-081908-5

D: Doran P., Bioprocess Engineering Principles, Academic Press, 1995, New York, 9780122208553

R: Shuler M. L., Kargi F., Bioprocess Engineering. Basic Concepts, Prentice Hall, Upper Saddle River, 2002, 0-13-081908-5

A: Doran P., Bioprocess Engineering Principles, Academic Press, 1995, New York, 9780122208553

Přednášky v elektronické podobě zveřejněné na www stránkách ústavu (www.vscht.cz/uchi)

Lecture notes available at www.vscht.cz/uchi

1. Introduction to the studies. Engineering and biological access to problem solving (production penicillin).

2. Basic piece of knowledge from cellulate biology.

3. Enzymes: classification, molecular structure, common characteristics and characteristics of enzymes.

4. Enzyme system kinetics, kinetic models, determination of kinetic parameters.

5. Immobilization of enzymes and microbial cells, used techniques and methods.

6. Transport processes in systems with immobilize enzymes. Manufacturing of enzymes, application of enzymes.

7. Simulation of kinetics microbial growth and performance metabolites, stoichiometry.

8. Influence of cultural conditions on kinetics of growth microbial cells.

9. Cellular growth and performance metabolites in batch cultures.

10. Cellular growth and performance metabolites in continuous cultures.

11. Fermenters, selection cultural method, bath and continuous bioreactors.

12. Simulation of fermenters, immobilize microbial cell, fermentation solid - state. Transmission masses.

13. Scale-up criteria, running and drive bioreactors. Simulation of bioreactors.

14. Aeration, sterilization.

Chemické inženýrství I

Unit operations of Chemical Engineering I

Student musí absolvovat dva testy během semestru (minimálně 25 bodů z 50 z každého testu).

Student must pass two tests in the course of semester (minimum 25 points out of 50 for each test).