SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Structural Analysis of Natural Compounds - M342003
Title: Strukturní analýza přírodních látek
Guaranteed by: Department of Chemistry of Natural Compounds (342)
Actual: from 2019
Semester: summer
Points: summer s.:3
E-Credits: summer s.:3
Examination process: summer s.:
Hours per week, examination: summer s.:2/0 Ex [hours/week]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
For type: Master's (post-Bachelor)
Additional information: http://intranet.vscht.cz/uchpl-intranet/6899/11238
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Drašar Pavel prof. RNDr. DSc.
Interchangeability : N342005
Examination dates   Schedule   
Annotation -
Last update: Kubová Petra Ing. (19.12.2017)
The course deals with analytical methods suitable for the analysis of natural compounds (products), namely IR, UV/VIS, NMR spectrometry, MS, chiroptical methods, and diffraction analysis.
Aim of the course -
Last update: Kubová Petra Ing. (19.12.2017)

Give a basic overview of methods and usage of analytical methods like IR, UV/VIS, MS , and NMR spectroscopy, chiroptical methods, and diffraction analysis

Choose an optimum combination of methods

Literature -
Last update: Kubová Petra Ing. (19.12.2017)

1. McMurry J., Organic Chemistry, 5th ed., Brooks Cole.

2. Ning Y.-C., Structural Identification of Organic Compounds with Spectroscopic Techniques, Wiley-VCH Weinheim 2005.

3. Mictchell T.N., Costisella B., NMR-From Spectra to Structures, Springer Berlin 2007.

4. Field L.D., Sternhell S., Kalman J.R., Organic Structures from Spectra, Wiley Chichester 2008.

5. Günther H., NMR Spectroscopy, Wiley VCH Weinheim 2013.

6. Watson J.T., Sparkman O.D., Instroduction to Mass Spectroscopy, Wiley Chichester 2007.

7. Ning Y.-C., Interpretation of Organic Spectra, Wiley Cichester 2011.

8. Silverstein R.M., Bassler G.C., Morrill T.C.: Spectrometric Identification of Organic Compounds, Fifth.Ed., John Willey and Sons, Inc. New York 1991. ( MS, IR, NMR, UV).

9. Stoddart J.F.: Stereochemistry v knize Comprehensive Organic Chemistry, Vol. I., str. 3; Pergamon Press Ltd., Oxford, 1979.

10. Stoddart J.F.: Stereochemistry of Carbohydrates, Willey-Interscience, New York 1971.

11. McLafferty F.W.: Interpretation of Mass Spectra, W.A.Benjamin,Inc. New York 1967.

12. http://www.spectroscopynow.com/

Learning resources -
Last update: Kubová Petra Ing. (19.12.2017)

http://www.spectroscopynow.com/view/index.html?tzcheck=1

Syllabus -
Last update: Kubová Petra Ing. (19.12.2017)

1. Overview of methods for structural analysis of natural compounds

2. Vibrational-rotational spectrometry

3. Raman spectrometry

4. Spectrometry in UV and visible region of light

5. 1H Nuclear magnetic resonance

6. Karplus equation and conformational study

7. NMR spectra interpretation

8. 13C Nuclear magnetic resonance

9. NMR applications for the study of chiral compounds

10. Mass spectrometry

11. Ionization methods, fragmentation paths

12. Chiroptical methods

13. Diffraction methods

14. Identification of an unknown compound

Registration requirements -
Last update: Kubová Petra Ing. (19.12.2017)

Bioorganic chemistry of natural compounds

Chemistry of natural compounds

Course completion requirements - Czech
Last update: MORAVCOJ (27.02.2018)

Předmět je zakončen samostatným projektem identifikace neznámé přírodní látky. Zkouška je ústní.

Coursework assessment
Form Significance
Regular attendance 20
Defense of an individual project 30
Oral examination 50

 
VŠCHT Praha