SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Structural Analysis of Natural Compounds - N342005
Title: Strukturní analýza přírodních látek
Guaranteed by: Department of Chemistry of Natural Compounds (342)
Actual: from 2018
Semester: summer
Points: summer s.:3
E-Credits: summer s.:3
Examination process: summer s.:
Hours per week, examination: summer s.:2/0 Ex [hours/week]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
For type:  
Additional information: http://intranet.vscht.cz/uchpl-intranet/6899/11238
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Drašar Pavel prof. RNDr. DSc.
Jurášek Michal Ing. Ph.D.
Is interchangeable with: M342003
Examination dates   Schedule   
Annotation -
Last update: TAJ342 (18.12.2013)
The course deals with analytical methods suitable for the analysis of natural compounds (products), namely IR, UV/VIS, NMR spectrometry, MS, chiroptical methods, and diffraction analysis.
Aim of the course -
Last update: TAJ342 (29.09.2013)

Give a basic overview of methods and usage of analytical methods like IR, UV/VIS, MS , and NMR spectroscopy, chiroptical methods, and diffraction analysis

Choose an optimum combination of methods

Literature -
Last update: Drašar Pavel prof. RNDr. DSc. (17.02.2016)

1. McMurry J., Organic Chemistry, 5th ed., Brooks Cole.

2. Ning Y.-C., Structural Identification of Organic Compounds with Spectroscopic Techniques, Wiley-VCH Weinheim 2005.

3. Mictchell T.N., Costisella B., NMR-From Spectra to Structures, Springer Berlin 2007.

4. Field L.D., Sternhell S., Kalman J.R., Organic Structures from Spectra, Wiley Chichester 2008.

5. Günther H., NMR Spectroscopy, Wiley VCH Weinheim 2013.

6. Watson J.T., Sparkman O.D., Instroduction to Mass Spectroscopy, Wiley Chichester 2007.

7. Ning Y.-C., Interpretation of Organic Spectra, Wiley Cichester 2011.

8. Silverstein R.M., Bassler G.C., Morrill T.C.: Spectrometric Identification of Organic Compounds, Fifth.Ed., John Willey and Sons, Inc. New York 1991. ( MS, IR, NMR, UV).

9. Stoddart J.F.: Stereochemistry v knize Comprehensive Organic Chemistry, Vol. I., str. 3; Pergamon Press Ltd., Oxford, 1979.

10. Stoddart J.F.: Stereochemistry of Carbohydrates, Willey-Interscience, New York 1971.

11. McLafferty F.W.: Interpretation of Mass Spectra, W.A.Benjamin,Inc. New York 1967.

12. http://www.spectroscopynow.com/

Learning resources -
Last update: TAJ342 (29.09.2013)

http://www.spectroscopynow.com/view/index.html?tzcheck=1

Syllabus -
Last update: TAJ342 (29.09.2013)

1. Overview of methods for structural analysis of natural compounds

2. Vibrational-rotational spectrometry

3. Raman spectrometry

4. Spectrometry in UV and visible region of light

5. 1H Nuclear magnetic resonance

6. Karplus equation and conformational study

7. NMR spectra interpretation

8. 13C Nuclear magnetic resonance

9. NMR applications for the study of chiral compounds

10. Mass spectrometry

11. Ionization methods, fragmentation paths

12. Chiroptical methods

13. Diffraction methods

14. Identification of an unknown compound

Registration requirements -
Last update: TAJ342 (29.09.2013)

Bioorganic chemistry of natural compounds

Chemistry of natural compounds

Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na zkoušku a její absolvování 2 56
3 / 3 84 / 84
Coursework assessment
Form Significance
Oral examination 100

 
VŠCHT Praha