SubjectsSubjects(version: 865)
Course, academic year 2019/2020
  
Analysis of Solid Pharmaceuticals - N108021
Title: Analýza pevných léčiv
Guaranteed by: Department of Solid State Chemistry (108)
Actual: from 2014
Semester: both
Points: 3
E-Credits: 3
Examination process:
Hours per week, examination: 2/0 Ex [hours/week]
Capacity: winter:54 / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
For type:  
Additional information: http://výuka probíhá pouze v zimním semestru
Note: course can be enrolled in outside the study plan
enabled for web enrollment
you can enroll for the course in winter and in summer semester
Guarantor: Čejka Jan Ing. Ph.D.
Annotation
Last update: TAJ108 (29.08.2013)
Lectures are focused on selected analytical methods used in pharmaceutical industry. Solid state techniques, polymorphism, solvatomorphism, mixtures, etc. are accented.
Aim of the course
Last update: TAJ108 (29.08.2013)

The students will be able to:

be oriented in basic crystallography and in selected analytical techniques;

choose optimal method to analyse API's or related impurities, considering the nature od the compounds either crystalline obr amorphous, polymorph transformations, co-crystals, mixtures, etc.;

analyse relative and absolute configuration.

Literature
Last update: TAJ108 (29.08.2013)

R:Kraus I.,Struktura a vlastnosti krystalů,Academia,Praha,1993,802000372X

Learning resources -
Last update: TAJ108 (06.09.2013)

Electronical version of study materials

Syllabus -
Last update: TAJ108 (29.08.2013)

1. Macroscopic assembly And symmetry od solid state compounds

2. Microscopic organization And symmetry in solid state

3. Single crystal X-ray analysis

4. X-ray powder analysis

5. Quality parameters of X-ray data, software available

6. Databases CSD, PDB, PDF

7. X-ray fluorescence analysis

8. Solid state NMR

9. IR and Raman spectroscopy

10. Thermal methods - TG, DTA, DSC, HSM, DVS

Excursions:

single crystal X-ray analysis

powder and fluorescence X-ray analysis

IR and Raman spectroscopy

Thermal methods

Entry requirements - Czech
Last update: Šmídová Ludmila (20.05.2009)

Pro zápis tohoto předmětu je nutno mít minimálně zapsán předmět N108022

Registration requirements -
Last update: TAJ108 (06.09.2013)

No pre-requisites

Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 1 28
3 / 3 84 / 84
Coursework assessment
Form Significance
Oral examination 100

 
VŠCHT Praha