SubjectsSubjects(version: 947)
Course, academic year 2023/2024
Pharmacochemistry - Z110001
Title: Farmakochemie
Guaranteed by: Department of Organic Chemistry (110)
Faculty: Faculty of Chemical Technology
Actual: from 2007
Semester: summer
Points: summer s.:3
E-Credits: summer s.:3
Examination process: summer s.:
Hours per week, examination: summer s.:2/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
For type:  
Additional information:
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Hampl František doc. Ing. CSc.
Is interchangeable with: M110001, N110001
Examination dates   Schedule   
Annotation -
Last update: SMIDOVAL (07.02.2007)
The aim of the lectures is to bring basic information in the chemistry of pharmaceuticals which should help the alumni to start their professional carrier in the pharmaceutical industry (R&D, manufacturing) and in the distribution of drugs. The introductory lectures cover general pharmaceutical chemistry: basic terms and definitions, principles of mutual drug and organism interactions, drug design methods, and good manufacturing practice. The main part of the lectures is devoted to systematic pharmaceutical chemistry giving a brief survey structures and syntheses of the most frequently used drugs. Obligatory pre-requisites: Organic Chemistry I and II. Recommended pre-requisites: Biochemistry I.
Literature - Czech
Last update: SMIDOVAL (07.02.2007)

F. Hampl, J. Paleček: Farmakochemie. Vydavatelství VŠCHT v Praze, 2002.

Syllabus -
Last update: SMIDOVAL (07.02.2007)

1. Introduction. Basic terms and definitions.

2. Mutual drug and organism interactions. Basic terms in pharmacology.

3. Drug design methods. Registration of drugs. Good manufacturing practice.

4. Analgesics, antipyretics, anti-inflammatory agents.

5. Central nervous system drugs: anaesthetics, sedatives, hypnotics.

6. Central nervous system drugs: psychiatric drugs.

7. Autonomous nervous system drugs: sympathomimetics and sympatholytics.

8. Autonomous nervous system drugs: parasympathomimetics and parasympatholytics. Local anaesthetics and muscle relaxants.

9. Antihistamines and antiallergics. Antitussives and expectorants.

10. Cardiovascular system drugs.

11. Digestive tract therapeutic agents.

12. Antiinfective agents.

13. Chemotherapy of cancer.

14. Vitamins a hormones.