SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Dosage Forms - M111016
Title: Lékové formy
Guaranteed by: Department of Organic Technology (111)
Actual: from 2019
Semester: summer
Points: summer s.:5
E-Credits: summer s.:5
Examination process: summer s.:
Hours per week, examination: summer s.:3/0 Ex [hours/week]
Capacity: unlimited / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
For type: Master's (post-Bachelor)
Guarantor: Zbytovská Jarmila doc.Mgr. Dr.rer.nat.
Interchangeability : N108023, N111054
Examination dates   Schedule   
Annotation -
Last update: Kubová Petra Ing. (04.01.2018)
The subject describes technologies of drug formulation. Particular drug forms are presented from the biological and physical-chemical point of view. Among others, the selection of excipients, drug formulation, quality and stability of dosage forms are discussed.
Aim of the course -
Last update: Kubová Petra Ing. (04.01.2018)

Students will be able to:

  • evaluate the pros and cons of the particular dosage forms in concrete cases, including manufacturing
  • understand issues of selection of appropriate excipients; know their classification and utilization
  • define the main issues of drug formulation and stability and their solving.

Literature -
Last update: Kubová Petra Ing. (04.01.2018)

R: aktuální Český lékopis

R: Komárek P., Rabišková M.: Technologie léků. Galén 2006. ISBN 80-7262-423-7.

A: Žabka M., Müller R.H., Hildebrand G.E.: Moderní lékové formy ve farmaceutické technologii. SAP Bratislava, 2001. ISBN 80-88908-43-4.

A: Aulton M.: Pharmaceutics: The Science of Dosage Form Design. Churchill Livingstone 2002. ISBN 0443055173.

A: Voigt R., Fahr A.: Pharmazeutische Technologie. Deutscher Apotheker Verlag, 2010. ISBN 9783769250039.

A: Bauer K.: Lehrbuch der Pharmazeutischen Technologie. Wissenschaftliche Verlagsgesellschaft, 2006. ISBN 9783804722224.

A: Ammon H.: Hunnius Pharmazeutisches Wörterbuch. De Gruyter Berlin, New York, 2010. ISBN 9783110206326.

Learning resources -
Last update: Kubová Petra Ing. (04.01.2018)

http://tresen.vscht.cz/kot/blog/tag/lekove-formy

Syllabus -
Last update: Kubová Petra Ing. (04.01.2018)

1. General definitions, classification of drug forms, pharmacopoeia and other standards.

2. Unit operations in drug manufacturing.

3. Biopharmaceutics.

4. Pharmaceutical excipients.

5. Oral administration I.: fluid dosage forms, powder dosage forms.

6. Oral administration II.: granules, capsules, tablets.

7. Parenteral administration I.: classification, injections.

8. Parenteral administration II.: infusions, implants and others.

9. Topical administration: dermal and transdermal fluid preparations.

10. Topical administration: dermal and transdermal semisolid preparations.

11. Dosage forms into the respiratory tract.

12. Ocular and auricular dosage forms.

13. Rectal, uretral and vaginal dosage forms.

14. Pharmaceutical packaging. Stability of pharmaceutical preparations.

Registration requirements -
Last update: Kubová Petra Ing. (04.01.2018)

none

Course completion requirements - Czech
Last update: Patera Jan Ing. Ph.D. (21.02.2018)

Studenti musí uspět ze zápočtového a následně zkouškového testu.

Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0,3 8
Účast na přednáškách 1,5 42
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 2,2 62
5 / 5 140 / 140
Coursework assessment
Form Significance
Examination test 80
Continuous assessment of study performance and course -credit tests 20

 
VŠCHT Praha