SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Dosage Forms - N111054
Title: Lékové formy
Guaranteed by: Department of Organic Technology (111)
Actual: from 2019
Semester: both
Points: 5
E-Credits: 5
Examination process:
Hours per week, examination: 3/0 Ex [hours/week]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
Is provided by: M111016
For type:  
Additional information: http://Výuka probíhá jen v letním semestru
Note: you can enroll for the course in winter and in summer semester
Guarantor: Zbytovská Jarmila doc.Mgr. Dr.rer.nat.
Patera Jan Ing. Ph.D.
Interchangeability : N108023
Is interchangeable with: M111016
This subject contains the following additional online materials
Annotation -
Last update: TAJ111 (30.08.2013)
The subject describes technologies of drug formulation. Particular drug forms are presented from the biological and physical-chemical point of view. Among others, the selection of excipients, drug formulation, quality and stability of dosage forms are discussed.
Aim of the course -
Last update: TAJ111 (30.08.2013)

Students will be able to:

  • evaluate the pros and cons of the particular dosage forms in concrete cases, including manufacturing
  • understand issues of selection of appropriate excipients; know their classification and utilization
  • define the main issues of drug formulation and stability and their solving.

Literature -
Last update: TAJ111 (30.08.2013)

R: aktuální Český lékopis

R: Komárek P., Rabišková M.: Technologie léků. Galén 2006. ISBN 80-7262-423-7.

A: Žabka M., Müller R.H., Hildebrand G.E.: Moderní lékové formy ve farmaceutické technologii. SAP Bratislava, 2001. ISBN 80-88908-43-4.

A: Aulton M.: Pharmaceutics: The Science of Dosage Form Design. Churchill Livingstone 2002. ISBN 0443055173.

A: Voigt R., Fahr A.: Pharmazeutische Technologie. Deutscher Apotheker Verlag, 2010. ISBN 9783769250039.

A: Bauer K.: Lehrbuch der Pharmazeutischen Technologie. Wissenschaftliche Verlagsgesellschaft, 2006. ISBN 9783804722224.

A: Ammon H.: Hunnius Pharmazeutisches Wörterbuch. De Gruyter Berlin, New York, 2010. ISBN 9783110206326.

Learning resources -
Last update: TAJ111 (30.08.2013)

http://tresen.vscht.cz/kot/blog/tag/lekove-formy

Syllabus -
Last update: TAJ111 (30.08.2013)

1. General definitions, classification of drug forms, pharmacopoeia and other standards.

2. Unit operations in drug manufacturing.

3. Biopharmaceutics.

4. Pharmaceutical excipients.

5. Oral administration I.: fluid dosage forms, powder dosage forms.

6. Oral administration II.: granules, capsules, tablets.

7. Parenteral administration I.: classification, injections.

8. Parenteral administration II.: infusions, implants and others.

9. Topical administration: dermal and transdermal fluid preparations.

10. Topical administration: dermal and transdermal semisolid preparations.

11. Dosage forms into the respiratory tract.

12. Ocular and auricular dosage forms.

13. Rectal, uretral and vaginal dosage forms.

14. Pharmaceutical packaging. Stability of pharmaceutical preparations.

Registration requirements -
Last update: TAJ111 (30.08.2013)

none

Teaching methods
Activity Credits Hours
Účast na přednáškách 1,5 42
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 2,5 70
5 / 5 140 / 140
Coursework assessment
Form Significance
Examination test 80
Continuous assessment of study performance and course -credit tests 20

 
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