Dosage Forms - M111016
Title: Lékové formy
Guaranteed by: Department of Organic Technology (111)
Faculty: Faculty of Chemical Technology
Actual: from 2019
Semester: summer
Points: summer s.:5
E-Credits: summer s.:5
Examination process: summer s.:
Hours per week, examination: summer s.:3/0, Ex [HT]
Capacity: 65 / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Zbytovská Jarmila doc. Mgr. Dr. rer. nat.
Interchangeability : N108023, N111054
Examination dates   
This subject contains the following additional online materials
Annotation -
The subject describes technologies of drug formulation. Particular drug forms are presented from the biological and physical-chemical point of view. Among others, the selection of excipients, drug formulation, quality and stability of dosage forms are discussed.
Last update: Kubová Petra (04.01.2018)
Aim of the course -

Students will be able to:

  • evaluate the pros and cons of the particular dosage forms in concrete cases, including manufacturing
  • understand issues of selection of appropriate excipients; know their classification and utilization
  • define the main issues of drug formulation and stability and their solving.

Last update: Kubová Petra (04.01.2018)
Literature -

R: aktuální Český lékopis

R: Komárek P., Rabišková M.: Technologie léků. Galén 2006. ISBN 80-7262-423-7.

A: Žabka M., Müller R.H., Hildebrand G.E.: Moderní lékové formy ve farmaceutické technologii. SAP Bratislava, 2001. ISBN 80-88908-43-4.

A: Aulton M.: Pharmaceutics: The Science of Dosage Form Design. Churchill Livingstone 2002. ISBN 0443055173.

A: Voigt R., Fahr A.: Pharmazeutische Technologie. Deutscher Apotheker Verlag, 2010. ISBN 9783769250039.

A: Bauer K.: Lehrbuch der Pharmazeutischen Technologie. Wissenschaftliche Verlagsgesellschaft, 2006. ISBN 9783804722224.

A: Ammon H.: Hunnius Pharmazeutisches Wörterbuch. De Gruyter Berlin, New York, 2010. ISBN 9783110206326.

Last update: Kubová Petra (04.01.2018)
Learning resources -

Last update: Kubová Petra (04.01.2018)
Syllabus -

1. General definitions, classification of drug forms, pharmacopoeia and other standards.

2. Unit operations in drug manufacturing.

3. Biopharmaceutics.

4. Pharmaceutical excipients.

5. Oral administration I.: fluid dosage forms, powder dosage forms.

6. Oral administration II.: granules, capsules, tablets.

7. Parenteral administration I.: classification, injections.

8. Parenteral administration II.: infusions, implants and others.

9. Topical administration: dermal and transdermal fluid preparations.

10. Topical administration: dermal and transdermal semisolid preparations.

11. Dosage forms into the respiratory tract.

12. Ocular and auricular dosage forms.

13. Rectal, uretral and vaginal dosage forms.

14. Pharmaceutical packaging. Stability of pharmaceutical preparations.

Last update: Kubová Petra (04.01.2018)
Registration requirements -


Last update: Kubová Petra (04.01.2018)
Course completion requirements - Czech

Studenti musí uspět ze zápočtového a následně zkouškového testu.

Last update: Patera Jan (21.02.2018)
Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0.3 8
Účast na přednáškách 1.5 42
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 2.2 62
5 / 5 140 / 140