Bioengineering I - N319008
Title: Bioinženýrství I
Guaranteed by: Department of Biotechnology (319)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2019 to 2020
Semester: winter
Points: winter s.:4
E-Credits: winter s.:4
Examination process: winter s.:
Hours per week, examination: winter s.:2/1, C+Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Is provided by: M319004
Guarantor: Halecký Martin doc. Ing. Ph.D.
Is interchangeable with: N320069, M319004, AM319004, S319008N
Examination dates   Schedule   
Annotation -
The course focuses on understanding and quantitative description of biological processes in the context of their implementation under defined conditions enabling to achieve reproducibility of results. The syllabus is based on the principles of kinetics, balancing as well as measurement and regulation of biological processes, including the design of the equipment.
Last update: Brányik Tomáš (21.08.2013)
Aim of the course -

Students will be able to:

Understand the biological, chemical and engineering processes in the biotechnology industry

Describe and evaluate basic biocatalytic processes.

Quantitatively evaluate experimental data of processes catalyzed by biological elements and to carry out heat and mass balances of biotechnological processes.

Design mixing and aeration equipment of bioreactors.

Last update: Brányik Tomáš (21.08.2013)
Literature -

R: Doran P.M.: Bioprocess Engineering Principles, Academic, London, 1995, ISBN: 9780122208553

R: Moo-Young M.: Comprehensive biotechnology, Elsevier B.V., 2011, ISBN: 9780080885049

A: Dunn I.J. et al.: Biological Reaction Engineering, Wiley-VCH, 2003, ISBN:9783527307593

A: Najafpour G.D.: Biochemical Engineering and Biotechnology, Elsevier B.V., 2007, ISBN 9780444528452

Last update: Brányik Tomáš (21.08.2013)
Learning resources -

Last update: Brányik Tomáš (21.08.2013)
Syllabus -

1. The issue of biotechnology and bioengineering.

2. The structure of bioprocess, equipment overview and unit operations.

3. Methods of optimization and modeling of biological processes.

4. Engineering kinetics of chemical and enzymatic reactions, kinetics of microbial growth.

5. Cultivation of microorganisms - batch and fed-batch cell cultures.

6. Cultivation of microorganisms - semicontinuous and continuous cell cultures.

7. Characteristics of phase folw - residence time distribution, flow models.

8. Mass transfer - oxygen transfer, aeration, measurement and quantification of KLa.

9. Specific aspects of plant/tissue cell and phototrophic cell cultivation.

10. Engineering aspects of enzyme and cell immobilization, biocatalysis.

11. Mixing in bioreactors - theory, power consumption, homogenization, shear forces.

12. Heat transfer, energy balance of bioreactors, sterilization, cooling and heating.

13. Scale-up of bioprocesses.

14. Construction materials, corrosion, design and construction of biotechnological processes.

Last update: Brányik Tomáš (29.09.2014)
Registration requirements -
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Last update: Kubová Petra (04.02.2020)
Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0.4 11
Obhajoba individuálního projektu 0.1 3
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 0.4 11
Práce na individuálním projektu 0.5 14
Příprava na zkoušku a její absolvování 1.1 30
Účast na seminářích 0.5 14
4 / 4 111 / 112
Coursework assessment
Form Significance
Regular attendance 10
Report from individual projects 10
Examination test 20
Oral examination 60