SubjectsSubjects(version: 875)
Course, academic year 2019/2020
Retrosynthesis - S110013
Title: Retrosynthesis
Guaranteed by: Department of Organic Chemistry (110)
Actual: from 2019
Semester: summer
Points: summer s.:6
E-Credits: summer s.:6
Examination process: summer s.:
Hours per week, examination: summer s.:3/1 Ex [hours/week]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: English
Teaching methods: full-time
Is provided by: AM110004
For type:  
Guarantor: Cibulka Radek prof. Ing. Ph.D.
Interchangeability : N110013
Z//Is interchangeable with: N110013, AM110004
Syllabus - Czech
Last update: KNOBLOCL (12.03.2012)

1. The disconnection approach. Basic principles.

2. Oxidation states of organic compounds.

3. One group C-X disconnections.

4. Two group C-X disconnections.

5. One group C-C disconnections: alcohols.

6. One group C-C disconnections: carbonyl compounds.

7. Alkene and alkyne synthesis.

8. Two group disconnections. 1,3- and 1,5-difunctionalised compounds.

9. Two group disconnections. 1,2-, 1,4- and 1,6-difunctionalised compounds.

10. Strategy of ring synthesis. Baldwin's rules. 3-, 4- and 5-membered rings.

11. Six-membered rings.

12. Heterocycles.

13. Stereoselective synthesis.

14. Linear and convergent synthesis.