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The course focuses on understanding and quantitative description of biological processes in the context of their implementation under defined conditions enabling to achieve reproducibility of results. The syllabus is based on the principles of kinetics, balancing as well as measurement and regulation of biological processes, including the design of the equipment.
Last update: Halecký Martin (16.09.2023)
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Students will be able to: Understand the biological, chemical and engineering processes in the biotechnology industry Describe and evaluate basic biocatalytic processes. Quantitatively evaluate experimental data of processes catalyzed by biological elements and to carry out heat and mass balances of biotechnological processes. Design mixing and aeration equipment of bioreactors. Last update: Halecký Martin (16.09.2023)
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Credit test (rated at least 50%). Exam test (rated at least 50%). Oral exam. Last update: Brányik Tomáš (23.01.2018)
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Recommended:
Last update: Brányik Tomáš (23.08.2024)
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1. The issue of biotechnology and bioengineering. 2. The structure of bioprocess, equipment overview and unit operations. 3. Methods of optimization and modeling of biological processes. 4. Engineering kinetics of chemical and enzymatic reactions, kinetics of microbial growth. 5. Cultivation of microorganisms - batch and fed-batch cell cultures. 6. Cultivation of microorganisms - semicontinuous and continuous cell cultures. 7. Characteristics of phase folw - residence time distribution, flow models. 8. Mass transfer - oxygen transfer, aeration, measurement and quantification of KLa. 9. Specific aspects of plant/tissue cell and phototrophic cell cultivation. 10. Engineering aspects of enzyme and cell immobilization, biocatalysis. 11. Mixing in bioreactors - theory, power consumption, homogenization, shear forces. 12. Heat transfer, energy balance of bioreactors, sterilization, cooling and heating. 13. Scale-up of bioprocesses. 14. Construction materials, corrosion, design and construction of biotechnological processes. Last update: Halecký Martin (16.09.2023)
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https://e-learning.vscht.cz/course/view.php?id=455 Last update: Halecký Martin (16.09.2023)
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Last update: Halecký Martin (16.09.2023)
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Teaching methods | ||||
Activity | Credits | Hours | ||
Konzultace s vyučujícími | 0.2 | 6 | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi | 0.5 | 14 | ||
Příprava na zkoušku a její absolvování | 1.8 | 50 | ||
Účast na seminářích | 0.5 | 14 | ||
4 / 4 | 112 / 112 |