SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Bioengineering I - N319008
Title: Bioinženýrství I
Guaranteed by: Department of Biotechnology (319)
Actual: from 2019
Semester: winter
Points: winter s.:4
E-Credits: winter s.:4
Examination process: winter s.:
Hours per week, examination: winter s.:2/1 C+Ex [hours/week]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
Is provided by: M319004
For type:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Halecký Martin doc. Ing. Ph.D.
Is interchangeable with: S319008N, M319004, AM319004
Annotation -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)
The course focuses on understanding and quantitative description of biological processes in the context of their implementation under defined conditions enabling to achieve reproducibility of results. The syllabus is based on the principles of kinetics, balancing as well as measurement and regulation of biological processes, including the design of the equipment.
Aim of the course -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)

Students will be able to:

Understand the biological, chemical and engineering processes in the biotechnology industry

Describe and evaluate basic biocatalytic processes.

Quantitatively evaluate experimental data of processes catalyzed by biological elements and to carry out heat and mass balances of biotechnological processes.

Design mixing and aeration equipment of bioreactors.

Literature -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)

R: Doran P.M.: Bioprocess Engineering Principles, Academic, London, 1995, ISBN: 9780122208553

R: Moo-Young M.: Comprehensive biotechnology, Elsevier B.V., 2011, ISBN: 9780080885049

A: Dunn I.J. et al.: Biological Reaction Engineering, Wiley-VCH, 2003, ISBN:9783527307593

A: Najafpour G.D.: Biochemical Engineering and Biotechnology, Elsevier B.V., 2007, ISBN 9780444528452

Learning resources -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)

http://eso.vscht.cz/predmety/N319008/

Syllabus -
Last update: Brányik Tomáš prof. Ing. Ph.D. (29.09.2014)

1. The issue of biotechnology and bioengineering.

2. The structure of bioprocess, equipment overview and unit operations.

3. Methods of optimization and modeling of biological processes.

4. Engineering kinetics of chemical and enzymatic reactions, kinetics of microbial growth.

5. Cultivation of microorganisms - batch and fed-batch cell cultures.

6. Cultivation of microorganisms - semicontinuous and continuous cell cultures.

7. Characteristics of phase folw - residence time distribution, flow models.

8. Mass transfer - oxygen transfer, aeration, measurement and quantification of KLa.

9. Specific aspects of plant/tissue cell and phototrophic cell cultivation.

10. Engineering aspects of enzyme and cell immobilization, biocatalysis.

11. Mixing in bioreactors - theory, power consumption, homogenization, shear forces.

12. Heat transfer, energy balance of bioreactors, sterilization, cooling and heating.

13. Scale-up of bioprocesses.

14. Construction materials, corrosion, design and construction of biotechnological processes.

Registration requirements -
Last update: Brányik Tomáš prof. Ing. Ph.D. (21.08.2013)

Chemical engineering

Microbiology

Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0,4 11
Obhajoba individuálního projektu 0,1 3
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 0,4 11
Práce na individuálním projektu 0,5 14
Příprava na zkoušku a její absolvování 1,1 30
Účast na seminářích 0,5 14
4 / 4 111 / 112
Coursework assessment
Form Significance
Regular attendance 10
Report from individual projects 10
Examination test 20
Oral examination 60

 
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