SubjectsSubjects(version: 954)
Course, academic year 2023/2024
Fundamentals of Toxicology and Ecology - N240011
Title: Základy toxikologie a ekologie
Guaranteed by: Department of Environmental Chemistry (240)
Faculty: Faculty of Environmental Technology
Actual: from 2019
Semester: both
Points: 3
E-Credits: 3
Examination process:
Hours per week, examination: 2/0, Ex [HT]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: cancelled
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Additional information: http://Předmět je vyučován pouze v zimním semestru. Zkoušky se konají u přednášejících.
Old code: ZTOE
Note: you can enroll for the course in winter and in summer semester
Guarantor: Kafka Zdeněk doc. Ing. CSc.
Punčochářová Jana RNDr. CSc.
Kochánková Lucie Ing. Ph.D.
Interchangeability : N111009, Z240011
Is interchangeable with: N111009, AB240001, B240001
Examination dates   Schedule   
Annotation -
Toxicology deals with chemical substances negative influence on living organisms. The aim of the lectures is to give basic information about hazardous chemical materials. The course presents the fate of hazardous chemicals in organisms, the type of their impacts on human being and their detrimental effects on tissues, organs,or biological processes. The relevant legislation is included. The characterization of special inorganic and organic compounds are described in details. The principles of occupational safety in chemical laboratory, first aid and prevention of accidents are covered. The part of ecology explains the hazardous compounds impact on the environment.
Last update: TAJ240 (18.11.2013)
Aim of the course -

Students will be able to understand:

  • The basic survey about toxicity and negative influence of certain chemical materials on human organism
  • The fate of xenobiotics in organism: entrance, distribution, biotransformation, excretion
  • The safe disposal with chemical substances and principles of first aid during accidents in chemical laboratory
Last update: TAJ240 (18.11.2013)
Literature -

R: Horák J., Linhart I., Klusoň P.: Úvod do toxikologie a ekologie pro chemiky, VŠCHT Praha, 2004, ISBN 80-7080-548-X

R: Linhart I.: Toxikologie: interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky, VŠCHT Praha, 2012, ISBN 978-80-7080-806-1

R: Relevant legislation

Last update: TAJ240 (25.09.2013)
Learning resources -

Electronical text-book

Úvod do toxikologie a ekologie pro chemiky

Horák Josef, Klusoň Petr, Linhart Igor


Last update: Kafka Zdeněk (12.08.2013)
Syllabus -

1. Introduction and structure of subject, history of toxicology, terms and definitions

2. General toxicology - effects of chemical compounds in details (nespecific toxic, biochemical, immunotoxic, mutagenic, cancerogenic, terratogenic)

3. General toxicology - xenobiotics in organism (barriers of entrance, entrance of compounds,distribution)

4. General toxicology - biotransformations of compounds(enzymes, basic reactions, factories), excretion(organs,influencing,factories, relations)

5. General toxicology - literature sources and experimental determination, legislation

6. Special toxicology - inorganic compounds by periodic table with s and p1, p2 elements

7. Special toxicology - inorganic compounds by periodic table with p3 a p4 elements(chalcogens)

8. Special toxicology - inorganic compounds by periodic table with p5 (halogens) and p6 (rare gases)

9. Special toxicology - organic compounds: hydrocarbons,derivatives with O,N,S and halogens

10. Compounds harm to the environment, bojové chemical compounds

11. Radioactive compounds, biotoxines (bacterial, myotoxines, mushroom, plant and animal poisons)

12. Drugs (sedativs, stimulants, halucinogens, psychotropic compounds); legislation

13. Disposal with chemicals, combustibles, prevention, fire and its extinguishment

14. Occupational safety in chemical laboratory, first aid

Last update: Kafka Zdeněk (13.08.2013)
Registration requirements -


Last update: Kafka Zdeněk (12.08.2013)
Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na zkoušku a její absolvování 2 56
3 / 3 84 / 84
Coursework assessment
Form Significance
Examination test 50
Oral examination 50